Category Archives: Cancer: Pancreatic

How obesity contributes to, blocks treatment of pancreatic cancer






Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which obesity increases inflammation and desmoplasia – an accumulation of connective tissue – in the most common form of pancreatic cancer. In their report published online in Cancer Discovery the … Continue reading






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Pancreatic cancer is 4 diseases, each with new treatment possibilities






An international team led by Australian researchers has studied the genetics of pancreatic cancer, revealing it is actually four separate diseases, each with different genetic triggers and survival rates, paving the way for more accurate diagnoses and treatments. The significant … Continue reading






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How obesity promotes pancreatic and breast cancer






Massachusetts General Hospital (MGH) investigators may have uncovered a novel mechanism behind the ability of obesity to promote cancer progression.  In their report published online in the journal Clinical Cancer Research, the research team describes finding an association between obesity … Continue reading






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How diabetes drug metformin inhibits progression of pancreatic cancer






Massachusetts General Hospital (MGH) investigators may have uncovered a novel mechanism behind the ability of the diabetes drug metformin to inhibit the progression of pancreatic cancer. In their report that has been published in the open access journal PLOS One, … Continue reading






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Magnesium may help pancreatic cancer prevention






Indiana University researchers have found that magnesium intake may be beneficial in preventing pancreatic cancer. Their study, “Magnesium intake and incidence of pancreatic cancer: The VITamins and Lifestyle study,” recently appeared in the British Journal of Cancer. Pancreatic cancer is … Continue reading






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Diet and Pancreatic Cancer Prevention






Cancers (Basel). 2015 Nov 23;7(4):2309-2317. Diet and Pancreatic Cancer Prevention. Casari I1, Falasca M2. Author information 1Metabolic Signalling Group, School of Biomedical Sciences, CHIRI Biosciences, Curtin University, Perth 6102, Australia. ilaria.casari@curtin.edu.au. 2Metabolic Signalling Group, School of Biomedical Sciences, CHIRI Biosciences, … Continue reading






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Pancreatic cancer, cigarettes, and alcohol






Alcohol Clin Exp Res. 2015 Oct 14. doi: 10.1111/acer.12882. [Epub ahead of print] Alcohol and Cigarette Smoke Components Activate Human Pancreatic Stellate Cells: Implications for the Progression of Chronic Pancreatitis. Lee AT1,2, Xu Z1, Pothula SP1, Patel MB1,2, Pirola RC1, … Continue reading






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Test for early stage pancreatic cancer could help save lives






University of Liverpool scientists, collaborating with a team at Bart’s Cancer Institute, have developed a urine test which could give an early diagnosis of pancreatic cancer. The test was developed as a result of a study led by Professor John … Continue reading






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Pancreatic cancer risk: new information from the Mayo Clinic






Newswise — JACKSONVILLE, Fla. — When people find out — usually from a diagnostic scan looking at something else — that they have a lesion in their pancreas that could morph into pancreatic cancer, they can panic. They insist on … Continue reading






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Cancer biopsies do not promote cancer spread






JACKSONVILLE, Fla. — A study of more than 2,000 patients by researchers at Mayo Clinic’s campus in Jacksonville, Florida, has dispelled the myth that cancer biopsies cause cancer to spread. In the Jan. 9 online issue of Gut, they show … Continue reading






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Blood Test May Help to Diagnose Pancreatic Cancer






Newswise — INDIANAPOLIS — Indiana University cancer researchers have found that a simple blood test might help diagnose pancreatic cancer, one of the most deadly forms of the disease. In research published today in the American Journal of Gastroenterology, Murray … Continue reading






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Pancreatic cancer linked to smoking in new study






New research that provides a better understanding of pancreatic cancer may help identify individuals at increased risk. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society. Pancreatic cancer is a stealthy cancer that … Continue reading






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Pancreatic cancer’s early signs






Newswise — BOSTON –– Scientists at Dana-Farber Cancer Institute, the Massachusetts Institute of Technology, and other institutions have discovered a sign of the early development of pancreatic cancer – an upsurge in certain amino acids that occurs before the disease … Continue reading






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Randomness of metastasis revealed by physicists






The spreading of a cancerous tumour from one part of the body to another may occur through pure chance instead of key genetic mutations, a new study has shown. Physicists from the University of Dundee and Arizona State University have … Continue reading






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Pancreatic cancer cells may be killed off with help of Chinese herbal extract






Bethesda, Md. (July 1, 2014) — A diagnosis of pancreatic cancer—the fourth most common cause of cancer death in the U.S.—can be devastating. Due in part to aggressive cell replication and tumor growth, pancreatic cancer progresses quickly and has a … Continue reading






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Four in 10 pancreatic cancers could be prevented by lifestyle changes






Almost 40 per cent of pancreatic cancers – one of the deadliest forms of cancer – could be avoided in the UK through maintaining a healthy weight and not smoking according to Cancer Research UK, in a call to arms … Continue reading






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Molecule linked to aggressive pancreatic cancer offers potential clinical advances






JACKSONVILLE, Fla. — Mayo Clinic researchers have discovered an enzyme they say is tightly linked to how aggressive pancreatic cancer will be in a patient. They say the study, published in Molecular Cancer Research, provides key insights into the most … Continue reading






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Pancreatic cancer spread could be slowed






CANCER RESEARCH UK scientists have shown how switching off a key protein in pancreatic cells slows the spread of the disease to other tissues, a key step which can mean patients have just weeks to live. The study, published in … Continue reading






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Pancreatic cancer’s ‘Achilles heel’ identified






WASHINGTON — A research team at Georgetown Lombardi Comprehensive Cancer Center reports that inhibiting a single protein completely shuts down growth of pancreatic cancer, a highly lethal disease with no effective therapy. Their study, published online today in Science Signaling, … Continue reading






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Diabetes and pancreatic cancer: a new link






In a new study published today in Annals of Surgical Oncology, clinicians worked with mathematicians to review data from 1973 to 2013 to conclude there was a time-dependent link between being diagnosed with diabetes and pancreatic cancer. A review of … Continue reading






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Pancreatic cancer biomarkers in blood show potential as early detection method






Researchers have identified diagnostic microRNA panels in whole blood that had the ability to distinguish, to some degree, patients with and without pancreatic cancer, according to a study in the January 22/29 issue of JAMA. The authors caution that the … Continue reading






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For pancreatic cancer, a potential new treatment






Scientists from The University of Manchester – part of Manchester Cancer Research Centre believe they have discovered a new way to make chemotherapy treatment more effective for pancreatic cancer patients. Pancreatic cancer is an aggressive cancer with poor prognosis and … Continue reading






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Pancreatic cancer could be caught early with blood test






Newswise — Reporting on a small preliminary study, Johns Hopkins researchers say a simple blood test based on detection of tiny epigenetic alterations may reveal the earliest signs of pancreatic cancer, a disease that is nearly always fatal because it … Continue reading






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Pancreatic cancer: 2-drug combination, nab-paclitaxel and gemcitabine, improves survival






Barcelona, 17 October 2013. A multicentre phase III study, with centers participating from 11 countries in North America, Europe and Australia, shows that the drug combination nab-paclitaxel and gemcitabine is more effective in the treatment of patients with advanced pancreatic … Continue reading






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Pancreatic cancer linked to high-fat, high-calorie diet






Researchers at UCLA’s Jonsson Comprehensive Cancer Center have found that mice made obese by high-calorie, high-fat diets develop abnormally high numbers of lesions known to be precursors to pancreas cancer. This is the first study to show a direct causative … Continue reading






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