Category Archives: Huntington’s

New Huntington’s Drug Deutetrabenazine (SD-809) Helps Reduce Involuntary Movements






People with Huntington disease (HD) experienced fewer involuntary movements, also known as chorea,  while taking deutetrabenazine (SD-809) compared to placebo, according to a paper published today in the Journal of the American Medical Association (JAMA). This study was supported by … Continue reading






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New Huntington’s Approach Could Lead To Significant Breakthrough






Most scientists doing research in this field view genes as being responsible for the disease in a direct causative way that goes from the gene to the protein product to a toxic influence on a cell, let’s say a neuron. … Continue reading






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Huntington’s onset: finding the factors






Researchers used a novel strategy to find genetic factors associated with the onset of Huntington’s disease symptoms. The approach may lead to ways to predict the onset and progression of disease as well as suggest new therapeutic approaches. Huntington’s disease … Continue reading






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First Huntington disease prevention trial shows treatment safety, suggests slowing of presymptomatic progression






Screening for Cognitive Impairment in Older Adults: An Evidence Update for the U.S. Preventive Services Task Force: Evidence Synthesis Number 107 The first clinical trial of a drug intended to delay the onset of symptoms of Huntington disease (HD) reveals … Continue reading






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The stem cell breakthrough that will allow faster, easier scientist access






A team of engineers at the University of Wisconsin-Madison has created a process to improve the creation of synthetic neural stem cells for use in central nervous system research. The process, outlined in a paper published in Stem Cells last … Continue reading






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Huntington’s drug reduces brain changes, motor deficits






WASHINGTON, DC — A drug that acts like a growth-promoting protein in the brain reduces degeneration and motor deficits associated with Huntington’s disease in two mouse models of the disorder, according to a study appearing November 27 in the Journal … Continue reading






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Antioxidant effect of resveratrol in the treatment of vascular dementia






Resveratrol, a polyphenolic compound, is synthesized in several plants and possesses beneficial biological effects, which include anti-oxidant, anti-inflammatory and anti-carcinogenic properties. Resveratrol exhibits neuroprotective effects in models of many diseases, such as cerebral ischemia, Huntington’s disease, Parkinson’s disease and Alzheimer’s … Continue reading






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Huntington’s disease progression can be tracked using PET scans






MANHASSET, NY – Investigators at The Feinstein Institute for Medical Research have discovered a new way to measure the progression of Huntington’s disease, using positron emission tomography (PET) to scan the brains of carriers of the gene. The findings are … Continue reading






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Huntington’s disease: a new clue on the origins






The synapses in the brain act as key communication points between approximately one hundred billion neurons. They form a complex network connecting various centres in the brain through electrical impulses. New research from Lund University suggests that it is precisely … Continue reading






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Alzheimer’s treatment keys may be found in Huntington’s






DURHAM, N.C., July 23, 2013 /PRNewswire/ — Huntington’s disease, or HD, an inherited brain disorder that affects roughly 30,000 people in the U.S., could hold the key to finding treatments or even a cure for Alzheimer’s and other major neurological disorders … Continue reading






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Huntington’s could be tracked with new biomarker






MENLO PARK, Calif.—July 8, 2013—A hallmark of neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Huntington’s is that by the time symptoms appear, significant brain damage has already occurred—and currently there are no treatments that can reverse it. A team of … Continue reading






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How stem cell materials could boost research into key diseases






Stem cell manufacturing for drug screening and treatments for diseases such as Huntington’s and Parkinson’s could be boosted by a new method of generating stem cells, a study suggests Stem cell manufacturing for drug screening and treatments for diseases such … Continue reading






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Neurodegenerative disease approach via metals: new information






MELBOURNE, AUSTRALIA-(Marketwire - Dec 5, 2012) - Prana Biotechnology (NASDAQ: PRAN) (ASX: PBT) today announced that leading scientists discussing the Metal Hypothesis at the New York Academy of Science on November 29th at a symposium titled “Targeting Metals in Alzheimer’s … Continue reading






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New Huntington’s therapy XJB-5-131 shows promise






There’s new hope in the fight against Huntington’s disease. A group of researchers that includes scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in … Continue reading






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New Huntington’s device has therapeutic potential






Studies suggest that neurotrophic factors, which play a role in the development and survival of neurons, have significant therapeutic and restorative potential for neurologic diseases such as Huntington’s disease. However, clinical applications are limited because these proteins cannot easily cross … Continue reading






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Huntington’s onset predicted by striatal brain volume






Huntington disease (HD) is an inherited neurodegenerative disorder caused by a defect on chromosome four where, within the Huntingtin gene, a CAG repeat occurs too many times. Most individuals begin experiencing symptoms in their 40s or 50s, but studies have … Continue reading






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Huntington’s cure may be possible via stem cells: new study






Huntington’s disease, the debilitating congenital neurological disorder that progressively robs patients of muscle coordination and cognitive ability, is a condition without effective treatment, a slow death sentence. But if researchers can build on new research reported this week (March 15, … Continue reading






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Early death, neurodegeneration linked to circadian rhythm disruption






New research at Oregon State University provides evidence for the first time that disruption of circadian rhythms – the biological “clocks” found in many animals – can clearly cause accelerated neurodegeneration, loss of motor function and premature death. The study … Continue reading






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Huntington’s slowed in Hopkins lab






Newswise — Working with genetically engineered mice, Johns Hopkins researchers have discovered that a gene (SIRT1) linked to slowing the aging process in cells also appears to dramatically delay the onset of Huntington’s disease (HD) and slow the progression of … Continue reading






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Is it OK to group ADHD, Alzheimer’s, depression, and Parkinson’s together?






It has become an NIMH mantra to describe mental disorders as brain disorders. What does this mean? Is it accurate to group schizophrenia, depression, and ADHD together with Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease? Is a neurologic approach to … Continue reading






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Hope for Parkinson’s, Huntington’s, Alzheimer’s in newly discovered compounds by Texas researchers






Investigators at Southern Methodist University and The University of Texas at Dallas have discovered a family of small molecules that shows promise in protecting brain cells against nerve-degenerative diseases such as Parkinson’s, Alzheimer’s and Huntington’s, which afflict millions. Dallas-based startup … Continue reading






Posted in Alzheimer's, Brain Fitness, Huntington's, Parkinson's | Tagged Aaron Heifetz, Alzheimer's, degenerative brain diseases, degenerative nerve disease, Edward R. Biehl, EncephRx, Huntington's, Inc., neurodegeneration, Parkinson's, small-molecule pharmaceuticals | Comments Off on Hope for Parkinson’s, Huntington’s, Alzheimer’s in newly discovered compounds by Texas researchers